fb Key Ingredients - Pipo Laboratorie

KEY INGREDIENTS

Apple amino acids

A natural, mild surfactant (tear-free) derived from apple amino acids. It gently removes impurities and excess sebum without disrupting the skin barrier. Ideal for sensitive skin, including baby skin and skin prone to irritation. Environmentally friendly and fully biodegradable.

Ectoin

An organic compound used by microorganisms to survive in extreme conditions. It acts as a powerful moisturizer and skin protector: it restores the barrier, reduces inflammation, alleviates symptoms of atopic dermatitis, and protects against UVA damage. Clinically proven effective, with results comparable to conventional therapy for moderate atopic dermatitis.

  • Marini A, et al. Ectoine-containing cream in the treatment of mild to moderate atopic dermatitis. Skin Pharmacol Physiol. 2014. link

  • Kauth M, Trusova OV. Topical Ectoine Application… Dermatol Ther (Heidelb). 2022. link

  • Wang Y, et al. The Reduction of Skin Photodamage by Ectoine. J Cosmet Dermatol. 2025. link

  • Buenger J, Driller H. Ectoin: an effective natural substance… Skin Pharmacol Physiol. 2004. link

  • Graf R, et al. The multifunctional role of ectoine. Clin Dermatol. 2008. link

  • Bownik A, Stępniewska Z. Ectoine as a promising protective agent… Arh Hig Rada Toksikol. 2016. link

Centella Asiatica Extract

A highly concentrated extract known for its powerful regenerative and anti-inflammatory properties. It restores damaged skin, stimulates collagen and elastin synthesis, and reduces redness and irritation. Helps with scars, acne, and sensitive skin.

  • Belcaro G, et al. TECA (Titrated Extract of Centella Asiatica)… Panminerva Med. 2011. link

  • Younis LT, et al. 3D TECA hydrogel… Asian J Pharm Sci. 2018. link

  • Park KS. Pharmacological Effects of Centella asiatica on Skin Diseases. Evid Based Complement Alternat Med. 2021. link

  • Lee Y, et al. Inhibitory Effect of Centella asiatica Extract… Nutrients. 2020. link

  • Ratz-Łyko A, et al. Moisturizing and Antiinflammatory Properties… Indian J Pharm Sci. 2016. link

Ceramides

Natural lipids that make up to 50% of a healthy skin barrier. PIPO creams contain as many as 7 different ceramides that work together to restore the lipid barrier, lock in moisture, and protect against allergens and irritants. Essential for dry and atopic skin, especially in babies.

  • Coderch L, et al. Ceramides and skin function. Am J Clin Dermatol. 2003. link

  • Meckfessel MH, Brandt S. The structure, function, and importance of ceramides… J Am Acad Dermatol. 2014. link

  • Yong TL, et al. Ceramides and Skin Health: New Insights. Exp Dermatol. 2025. link

Cold-Pressed Hemp Oil

Rich in essential fatty acids (omega-3 and omega-6). It improves skin elasticity, firmness, and resilience, promotes healing, and reduces inflammation. Particularly valuable in the care of dry and atopic skin.

  • Vitek M, Matjaž MG. Clinical application of hempseed or flaxseed oil… Acta Pharm. 2024. link

  • Martins AM, et al. Cannabis-Based Products for the Treatment of Skin Inflammatory Diseases. Pharmaceuticals (Basel). 2022. link

  • Žugić A, et al. Comprehensive Insight into Cutaneous Application of Hemp. Pharmaceutics. 2024. link

Bio microalgae oil

A luxurious oil from Schizochytrium sp. microalgae, rich in omega-9 fatty acids (>>90%). It protects the lipid barrier, provides hydration, improves elasticity, and reduces UV damage. Ecologically sustainable, pure, and stable.

Centella oil macerate (Gotu kola)

A botanical macerate rich in regenerative and soothing compounds (asiaticoside, flavonoids). It helps with scars, stretch marks, and irritation, improves skin texture, and stimulates collagen production. Safe for pregnant and breastfeeding women.